Urban and Rural Disparities in Pneumococcal Carriage and Resistance in Jordanian Children, 2015–2019

Background: A pneumococcal carriage surveillance study took place examining Jordanian children in urban and rural areas the period 2015–2019. Objectives: To determine differences rate, resistance, serotypes among healthy from Amman (urban) eastern Madaba (rural). Methods: Nasopharyngeal swabs (NP) were taken 682 aged 1 to 163 months. Pneumococcal identification, serotyping, resistance performed according standard method. Results: The number of cases tested for was 267 there 415 Madaba. Carriage rate 39.5% 31.1% Amman. Predominant 19F (21.3%; 15.7%), 23F (12.2%; 9.6%), 14 (6.7%; 2.4%), 19A (4.9%; 6A (5.5%; 3.6%). Resistance rates as follows: penicillin (95.8%; 81.9%), clarithromycin (68.9%; 59.0%), clindamycin (40.8%; 31.3%), trimethoprim-sulfamethoxazole (73.2%; 61.4%). Coverage PCV7, PCV13, future PCV20 42.2%, 48.2%, 60.2%; Madaba, coverage 50.0%, 62.2%, 73.2%, respectively. In 25.8% received 1–3 PCV7 injections compared 1.9% Conclusions: There significant carriage, between both regions. potential inclusion a PCV vaccination program is essential.